Lady Gaga will make her performing debut on The Late Show with David Letterman on Wednesday night.
While she's appeared on the show before -- for an interview, back in 2011 -- this will be the first time she's ever actually sung on the show. She'll be all warmed up, too, since she's currently in the middle of her seven-night stand at New York's Roseland Ballroom. When she does her final show there on April 7, the venue will close its doors forever.
Copyright 2014 ABC News Radio