Leto is returning to the big screen for upcoming drama The Dallas Buyers Club, starring as an HIV-positive cross dresser, alongside Matthew McConaughey and Jennifer Garner.
The star has already begun making painful changes as he prepares to shoot his scenes - he visited a beauty salon to have his body hair ripped off and his eyebrows plucked.
Taking to his Twitter.com account to share his treatments with fans, he writes, ""I just waxed my legs for this new role. Time to get into character. Pluck pluck pluck. Filming this week.
""Ladies, I feel your pain. What I have learned today: Beauty is pain. Wax on wax off.""
After the beautician tackled his bushy brows, he added, ""Oh s**t, there go the eyebrows!!!""
The film features McConaughey as Rod Woodroof, a Texas electrician who smuggled AIDS drugs into America.